Altered VEGF mRNA Stability following Treatments with Immunosuppressive Agents

Cytotoxic Agents with Immunosuppressive Activity

A whole variety of chemical and biological materials have immunosuppressive effects in animals. Although anti-inflammatory agents, especially the corticosteroids, are inhibitors of the immune response, most are general cytotoxic agents. The cytotoxic agents were first developed as antitumour agents. It is now well known that they are not particularly selective for cancer cells, but are selectiv...

Cytomegalovirus upon Treatment with Immunosuppressive Agents

Splenic lymphocytes from cytomegalovirus-infected mice lost their in vitro proliferative responses to cytomegalovirus antigen within 3 h after in vivo treatment with antilymphocyte globulin and prednisolone. The response was inhibited when the agents were administered separately or together, and inhibition persisted through a 2-week course of immunosuppression. Circulating specific antibodies w...

Problems with immunosuppressive agents in renal disease.

Pharmacological immunosuppressive agents.

A vast range of different compounds seem capable of depressing the immune response, however, it has been disappointing that so few of these have shown potential as immunosuppressive agents in man. The action of many has been to suppress lymphocyte reactivity in vitro and of those that are capable of prolonging graft survival in animals in addition, just a handful have been found to be safe and ...

[Immunosuppressive agents in Dermatology].

Immunosupressants are drugs that act in cell division and have anti-inflammatory effects. Therefore, they are essentially prescribed in the prevention of transplant rejection and in the treatment of autoimmune disorders and chronic inflammatory diseases, whose main example in Dermatology is psoriasis. In this work the most important immunosuppressive drugs and orientation to properly administer...